The Prisoner's Dilemma is not only useful in describing the problem, but also serves as a way to organize solutions. We humans have developed four basic mechanisms for ways to limit defectors: what I call societal pressure. We use morals, reputation, laws, and security systems. It's all coercion, really, although we don't call it that. I'll spare you the details; it would require a book to explain.
Mr. Bruce Schneider  wrote an essay book on security.
You might find more details here.
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